Hodgkin disease

Hodgkin disease

 or lymphoreticuloma

Most common malignant lymphoma. It starts with local, painless swelling of lymph nodes and sometimes of the spleen, liver, or other organs, followed by weight loss and weakness. Diagnosis can be confirmed only by biopsy, usually from a lymph node. The cause remains unknown. Treatment with chemotherapy, radiation, or both depends on the stage of the disease. More than 90% of patients diagnosed early can be cured, as can many with advanced disease.