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homeobox
(redirected from Homeodomain protein)

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homeobox [′hō·mē·ə‚bäks]
(cell and molecular biology)
A highly conserved sequence of deoxyribonucleic acid (DNA) that occurs in the coding region of development-controlling regulatory genes and codes for a protein domain that is similar in structure to certain DNA-binding proteins and is thought to be involved in the control of gene expression during morphogenesis and development.
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LEDGF appears to be important during embryonic development, since the majority of homozygous LEDGF KO mice die perinatally and survivors display a range of abnormal phenotypes, compatible with defects in homeodomain proteins [84].
Targeting the HIV integration process in antiviral therapy by McNeely, Melissa; Christ, Frauke; Thys, Wannes; Debyser, Zeger / Journal of HIV Therapy
The caudal-related homeodomain protein Cdx-2 regulates vitamin D receptor gene expression in the small intestine.
The vitamin D receptor gene and osteoporosis by Xuereb-Anastasi, Angela; Vidal, Christopher / Clinical Dermatology
Selleri researches the developmental contributions of human proto-oncogenes with a focus on the biological functions of Pbx1, a homeodomain protein originally identified as the product of an oncogene in childhood leukemias.
Multiplex Gene Expression HD2 12x135K Microarrays Now Available from ... by Business Wire
 
 
 
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