homodimer


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Related to homodimer: Heterodimer

homodimer

[‚hō·mō′dī·mər]
(biochemistry)
A protein made of paired identical polypeptides.
References in periodicals archive ?
For this study, in order to estimate the feasibility of scaffold QS/FGS, the essay "Live/Dead" with homodimer calceina- ethidium was used, in which the medium was removed to evaluate and saline phosphate (PBS) was added; the cell sample was washed to remove or dilute any residue supplemented, the PBS was removed with care not to dislodge the cells, 0.
Gel filtration chromatography also showed that the recombinant enzyme existed both as homodimer as well as homotetramer with the dimer being the more abundant form.
It was designed and engineered to stimulate specifically the erythropoiefin receptor homodimer that governs erythropoiesis.
EPO 'classically' binds to two EPORs which become joined as a homodimer and change.
At San Antonio, in an oral presentation, entitled HER2 Protein expression and homodimer levels predict response to trastuzumab in centrally tested FISH-positive metastatic breast cancer patients," Allan Lipton M.
platelet derived growth factor receptor protein which preferentially binds to the AA homodimer and AB heterodimer forms of platelet derived growth factor and also binds the BB homodimer at high affinity, is described.
This channel is a complex homodimer that conducts chloride ions over the entire physiological voltage ranges and is consequently the major mediator of chloride conductance in the skeletal muscle (Esteban et al.
The functional CaR on the cell surface forms a homodimer through covalent intermolecular disulphide bonds between cystein residues in the ECD and is considered to contribute to the high degree of receptor cooperativity (12,13).
The IgG anti-HEV assay used in the study was produced with a recombinant peptide of the major HEV structural protein that occurs naturally as a homodimer (36).
To date, an extensive set of x-ray crystal structures of HIV-1 protease have been solved, revealing a symmetric homodimer with a large substrate binding pocket covered by two glycine-rich [beta]-hairpins, or flaps.
The enzyme is a homodimer with each mature subunit of 41.
Creatine kinase (CK) is a 86 kDa homodimer that catalyzes the reversible synthesis of adenine triphosphate (ATP) from the hydrolysis of phosphocreatine to creatine.