It has been shown that amine oxidases are homodimeric
enzymes that contain two active centres per one molecule.
The obligate aerobic bacterium, Vitreoscilla, synthesizes elevated quantities of a homodimeric
hemoglobin (VHb) under hypoxic growth conditions.
GCSF acts on its homodimeric
receptor (GCSFR) to stimulate proliferation of granulocytic progenitor cells and induce their survival and differentiation into neutrophils.
Furthermore, FASN encodes fatty acid synthase, which forms a complex homodimeric
enzyme and plays an important role in biosynthesis of long chain fatty acids from acetyl coenzyme A (CoA) and malonyl-CoA (Semenkovich et al.
Prolidase is a manganese(Mn)-requiring homodimeric
iminodipeptidase that releases carboxy-terminal proline or hydroxyproline from oligopeptides.
The result is in agreement with previous findings in which the biological active hBMP-7 was described as homodimeric
or heterodimeric forms (3), (30), (31).
complex of HLA-G on normal trophoblast cells modulates antigen-presenting cells via LILRB1.
laccase with unique characteristics from the yellow mushroom Cantharellus cibarius.
glycoprotein of-- 90kDa is expressed in most cells except mature erythrocytes.
Galectin-1 is a multifunctional homodimeric
lectin whose extracellular and intracellular activities are thought to regulate cellular processes as diverse as cell--matrix interactions, signal transduction, migration, differentiation, proliferation, apoptosis, and RNA splicing (Hughes 2001; Liu et al.
Cysteine biosynthesis is catalyzed by a bifunctional complex composed of two molecules of homodimeric
O-acetylserine sulfhydrase and one molecule of homotetrameric serine acetyl-transferase (Droux et al.
Molecular dynamics simulations and docking studies on 3D models of the heterodimeric and homodimeric
5-HT2A receptor subtype Agostino Bruno, Claudia Beato, Gabriele Costantino