Upon JH binding to the PAS-B domain, Met undergoes a conformational change that liberates Met from the homodimer
complex and allows it to bind Taiman [43,45-47].
It was found that Rv2625c-Rv2624c and Rv2626c-Rv2625c are transcribed in dicistronic messengers, that there is a promoter in the Rv2626c upstream region, and that Rv2625 and Rv2626 proteins form homodimers
The tissue protective effects of EPO may be elicited through the EPOR homodimer
via JAK2-STAT5 activation and mediation of apoptosis.
HLA-B27 heavy chain proteins can form covalent homodimers
which are expressed on the cell surface.
Some TLRs form hetero (TLR2/TLR1, TLR2/TLR6) or homodimers
There are three major CK isoenzymes; the two homodimers
CK-MM and CK-BB and the heterodimer CK-MB.
The complex diversity and pleiotropic effects in the retinoid signaling pathway are provided not only due to existence of multiple isoforms of RARs but also as a result of combinations of RAR-RXR heterodimers or homodimers
and the presence of different ligands [14,17].
The retrospective study is designed to compare conventional IHC and FISH methods of HER2 testing with the quantitative measurements of HER2 total protein and HER2 homodimers
provided by Monogram's HERmark Breast Cancer Assay.
The steroid receptors in general work as homodimers
, while other receptors (those for thyroid hormones, vitamin D and RAR) operate as heterodimers with RXR.
These authors also claim that such receptors may form hetero- or homodimers
due to non-covalent interactions, causing protein bands higher than 200 kDa on the blots.
The three class I genes, ADH1A, ADH1B, and ADH1C, are very closely related; they encode the [alpha], [beta], and [gamma] subunits, which can form homodimers
or heterodimers (3) that account for most of the ethanol-oxidizing capacity in the liver (Hurley et al.
An excess of Bax lead to formation of more Bax-Bax homodimers
, leading to release of cytochrome C and activation of Apaf -1.