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Howard Hughes Medical Institute

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Howard Hughes Medical Institute, (HHMI), nonprofit medical research organization founded in 1953 by Howard Hughes Hughes, Howard Robard, 1905–76, U.S. business executive, b. Houston. As a young man he inherited (1925) the patent rights to an oil tool drill, which, manufactured by the Hughes Tool Company, formed the basis of his financial empire.
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 and largly funded from proceeds of the 1984–85 sale of Hughes Aircraft. Headquartered in Chevy Chase, Md., it is one of the world's largest and wealthiest philanthropies. HHMI supports the research of several hundred "investigators," largely geneticists and biologists, at universities, hospitals, and laboratories throughout the United States; it also has an international program. HHMI also provides funds for labs and equipment, and in all grants about $1 million per researcher. In 2006 HHMI opened a new scientific research campus, Janelia Farm, at Ashburn, Va. There groups of researchers—biologists, geneticists, computer scientists, engineers, physicists, and others—undertake basic biomedical research that requires input from a variety of areas as well as long-term effort or that is outside the scope of other funders.


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Shulman, an endocrinologist at the Howard Hughes Medical Institute and Yale University School of Medicine.
Researchers at the Howard Hughes Medical Institute find a genetic link between a high-fat diet and the onset of type 2 diabetes.
Bert Vogelstein and colleagues at the Johns Hopkins Kimmel Cancer Center and Howard Hughes Medical Institute, in a collaborative study with Indivumed, have developed a test that reliably quantifies mutations in cancer genes in the blood of colorectal cancer patients (F.
 
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