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progeria |
Also found in: Dictionary/thesaurus, Medical, Wikipedia, Hutchinson | 0.38 sec. |
progeriaDisorder with characteristics of premature aging. Affected persons have thin skin, go bald or gray early, and develop diseases of aging decades earlier than normal individuals. Not all systems are affected; there is no senility, no aging in the central nervous system. There are two major types. In the extremely rare Hutchinson-Gilford syndrome, children look 60 years old by age 10 and die at an average age of 13. The unrelated Werner syndrome is a recessive hereditary disease that begins in young adulthood and makes patients look 30 years older than they are; their average life span is 47 years. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| This PA is a new initiative to support research to understand how mutations in the gene for lamin A/C affect nuclear structure, thus leading to bothdysfunction of the nuclear envelope, and depending on the mutation, Hutchinson-Gilford syndrome in humans (Eriksson et al. These range from Down Syndrome (1 in 660 live births) to Hutchinson-Gilford Syndrome (1 in 250,000 live births). |
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