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hybridization probe

   Also found in: Medical, Wikipedia 0.03 sec.
hybridization probe [‚hī·brəd·ə′zā·shən ′prōb]
(cell and molecular biology)
A small molecule of deoxyribonucleic acid or ribonucleic acid that is radioactively labeled and used to identify complementary nucleic acid sequences by hybridization.


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They are useful when it is either not possible or desirable to isolate the probe-target hybrids from an excess of the hybridization probes, such as in the real-time monitoring of PCRs in sealed tubes or when detecting ribonucleic acid within living cells.
Lee also questions the scientific basis for approval of the HPV-16 and HPV-18 genotyping based on hybridization probes because in a previous ruling by Dr.
 
 
 
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