hydrazone

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hydrazone

[′hī·drə‚zōn]
(organic chemistry)
A compound containing the grouping ‒NH·N:C‒, and obtained from a condensation reaction involving hydrazines with aldehydes or ketones; has been used as an exotic fuel.
References in periodicals archive ?
Results demonstrated that the heterocyclic hydrazones also caused a reduction in CDK4 expression.
The Preparation of Pyrazole-Carboxylic Acids by the Condensation-Cyclization of the 1,4-Dianions of Substituted Hydrazones with Carboxylic Acid Anhydrides.
Kinetic constants of vulcanization reaction in presence of aldehyde phenyl hydrazones and benzophonene amine derivatives in NR mixes As the vulcanization reaction, crosslinking can be considered as a first order chemical reaction.
It is remarkable that besides traditional polymer materials a strong position has been won by a new class of functional materials: electrically conductive polymers and organic charge-transporting materials, hydrazones.
RCC derivatives are further converted into their corresponding hydrazones, which can be separated and analyzed by GC-MS or HPLC (64, 65).
In preclinical studies, Vion is also evaluating VNP40541 (formerly KS119W), a hypoxia-selective compound from the sulfonylhydrazine class, and heterocyclic hydrazones.
The 1,4-dianions of hydrazones, such as 4'-mehoxyacetophenone phenylhydrazone or 4'-bromoacetophenonre carbomethoxyhydrazone, were prepared in excess lithium diisopropylamide and condensed with phthalic or 1,2-cyclohexanedicarboxylic anhydride, to give C-acylated intermediate that could be isolated or cyclized to the expected pyrazole-carboxylic acid.
Vion is also developing and has an option to license several heterocyclic hydrazones which have demonstrated potent anti-tumor activity in preclinical studies.
In preclinical studies, Vion is also evaluating KS119W, a hypoxia-selective compound from the sulfonylhydrazine class, and heterocyclic hydrazones.
9:45 The Preparation of 5-Isoxazolecarboxamides and Related Compounds from the Condensation and Cyclization of Dilithiated Oximes or Polylithiated Hydrazones with Polylithiated Oxanilates, J.