In this study chemically crosslinked PEGDMA hydrogels
were synthesised by means of photopolymerisation.
To prepare ELP-collagen hydrogels
, 25 mg ELP, DI water (160 L), 10 X PBS (200 L), 1 N NaOH (40 L), and type I collagen (rat tail, 1.
Like gelatin, early versions of the hydrogels
would fall apart, whereas human hearts are elastic.
It has been often suggested that integration of the silicone-based materials with organic, tissue-like hydrogel
materials should enhance functionality," said group leader Hyunjoon Kong, assistant professor of chemical and biomolecular engineering.
According to the literature survey based on Chemical Abstract Service, a few studies have been reported in the case of protein-based hydrogels
(Branco et al.
Aoyagi and his colleagues then loaded hydrogel
with o-NBA and L-DOPA, a precursor of the brain chemical dopamine that is used in the treatment of Parkinson's disease.
Two-stepped methodology was used for IPN hydrogels
Besides physiological proteins present in the brain, the hydrogel
has the synthetic adhesive molecule IKVAV.
contract and expand in different water temperatures, Franck Vernerey, a mechanical engineer at the University of Colorado Boulder, has begun experimenting with making a device that squirms through water.
The strategy of creating entirely protein-based hydrogels
represents a new way to design bioactive materials with precise control over their properties.
Macroporous PAAm hydrogels
are typically synthesized by methods that make use of cryogelation [20, 21], porogens [22-24], or reaction-induced phase separation .
But his team has gone a step further by identifying properties that would be useful in treating heart attack patients and then designing hydrogels
with those properties.