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scar
(redirected from Hypertrophic scar)

   Also found in: Dictionary/thesaurus, Medical, Acronyms, Wikipedia 0.09 sec.
scar, fibrous connective tissue connective tissue, supportive tissue widely distributed in the body, characterized by large amounts of intercellular substance and relatively few cells. The intercellular material, or matrix, is produced by the cells and gives the tissue its particular character.
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 that forms at the site of injury or disease in any tissue of the body. Scar tissue may replace injured skin and underlying muscle, damaged heart muscle, or diseased areas of internal organs such as the liver. Dense and thick, it is usually paler than the surrounding tissue because it is poorly supplied with blood, and although it structurally replaces destroyed tissue, it cannot perform the functions of the missing tissue. Scar tissue may therefore limit the range of muscle movement or prevent proper circulation of fluids when affecting the lymphatic or circulatory system. Extensively scarred tissue may lose its ability to function normally.

scar

Mark left on the skin after a wound heals. Cells called fibroblasts produce collagen fibres, which form bundles that make up the bulk of scar tissue. Scars have a blood supply but no oil glands or elastic tissue, so they can be slightly painful or itchy. Hypertrophic scars grow overly thick and fibrous but remain within the original wound site. Scars can also develop into tumourlike growths called keloids, which extend beyond the wound's limits. Both can inhibit movement when they result from serious burns over large areas, especially around a joint. Scars, especially those from unaided healing of third-degree burns, can become malignant. Treatment of serious scars is one of the most important problems in plastic surgery.


scar1
1. any mark left on the skin or other tissue following the healing of a wound
2. the mark on a plant indicating the former point of attachment of a part, esp the attachment of a leaf to a stem

scar2
1. an irregular enlongated trench-like feature on a land surface that often exposes bedrock
2. a similar formation in a river or sea


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Scar formation after cutaneous trauma, surgical or otherwise, encompasses a broad spectrum, ranging from normal scars to hypertrophic scars to keloids.
The removable gel pad helps cushion, absorb, and redistribute external pressure exerted on the injured thumb, and it releases medical-grade mineral oil to help reduce and prevent hypertrophic scar formation after the removal of sutures.
Immusol's lead drug candidate, ChelASE, is being studied in phase II clinical trials for the treatment of keloids and hypertrophic scars.
 
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