The clinical presentation of hypokalemic
quadriparesis with respiratory failure as the first manifestation of pSS is very atypical.
patients then receive oral potassium if their potassium level was 2.
Potassium is the major intracellular electrolyte and the relationship between its intracellular and extracellular levels is the main determinant of the electric potential of the membranes; any significant change in extracellular potassium concentration can therefore have effects not only on metabolic functions, but also in nerve conduction, with muscular repercussions; hypokalemic
polymyopathy is a reflection of this.
patients with excessive renal potassium excretion, rare genetic tubulopathies, such as Gitelman syndrome and Bartter syndrome, should be considered.
The screening should include hypokalemic
and normokalemic patients (although the exact data is difficult to quantify given the lack of high-powered randomized controlled trials, current research is finding greater prevalence of PA without hypokalemia), as it is widely noted in the literature that hypokalemia has a low sensitivity and positive predictive value for PA.
Gitelman's syndrome (GS) is an inherited hypokalemic
salt-losing tubulopathy with secondary hyperaldosteronism that affects the thiazide-inhibitable sodium-chloride cotransporter (NCCT) of the distal tubule, making its presentation similar to that of treatment with thiazide diuretics.
More extreme presentations have also been reported, with many associated complications including hypokalemic
EKG changes, atrial fibrillation, myxedema, renal tubular acidosis, nystagmus, deafness, and deaths from cardiac and respiratory depression.
Pharmaceutical company Taro Pharmaceutical Industries (NYSE:TARO) disclosed on Monday the launch of Keveyis (dichlorphenamide) 50 mg Tablets for the treatment of primary hyperkalemic and hypokalemic
periodic paralysis and related variants in the US market.
Herein, we report another case of concurrent bipolar mania and hypokalemic
periodic paralysis (HPP).
Hawkins (15) studied the hemolysis frequency in whole blood gas analysis in his clinical laboratory and found that hemolysis was more than 5 times higher in whole blood used for blood gases compared with serum and that 42% of potassium results in these specimens were downgraded from normokalemic to hypokalemic
or from hyperkalemic to normokalemia or hypokalemic
An unusual cause of hypokalemic
paralysis: aristolochic acid nephropathy with Fanconi syndrome.
Based on our patient's paralysis, hyperthyroidism, and hypokalemia, we diagnosed thyrotoxic hypokalemic
periodic paralysis (THPP), a rare endocrinopathy that causes electrolyte disturbances that can result In paralysis and lethal tachyarrhythmias.