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Condition caused by insufficient secretion of pituitary hormones, especially of the adenohypophysis. Also known as panhypopituitarism.



a chronic condition caused by reduced internal secretion of the pituitary body.

Hypopituitarism is manifested by insufficiency of function of the thyroid, adrenal cortex, and gonads. Trauma, tumors, infections, and hemorrhages in the area of the base of the brain can result in hypopituitarism. Hypopituitarism is manifested in arrested growth (nanism), impairment of lipometabolism, causing obesity or severe emaciation (cachexia), or underdevelopment of the sexual organs. In women with hypopituitarism, menstruation ceases and the uterus, ovaries, and mammary glands atrophy. In men the testicles and penis atrophy. Physical and mental languor, frequent dizziness, buzzing in the ears, headaches, sleepiness, susceptibility to fatigue, and a lowering of the basal metabolism are characteristic of hypopituitarism. Pituitary tumors are treated by X-ray and radiotherapy or surgical operation; other forms are treated by hormonal therapy.


References in periodicals archive ?
Most of the patients who present with apoplexy have a hypopituitarism with decreased levels of all or several pituitary hormones.
A case of intrasellar and suprasellar meningioma with hypopituitarism.
The doctors at AIIMS's endocrinology department diagnosed the two with hypopituitarism.
The investigators excluded patients with primary hypogonadism, surgical gonadectomy, and medical conditions such as anorexia nervosa, hypothyroidism, and hypopituitarism that could lead to hypogonadism.
Hyper- and hypo-thyroidism (thyroid hormones) Hypercalcemia (calcium) Hyper- and hyponatremia (sodium) Hypoglycemia (glucose) Hyperlipidemia (lipids) Hypercapnia (carbon dioxide) Kidney failure Liver failure Cushing syndrome Addison's disease Hypopituitarism Remote effect of carcinoma
No data are available on leukemia rates among untreated, hypopituitary patients, leaving open the possibility the leukemia link may result from an underlying genetic condition associated with hypopituitarism rather than the hGH treatment.
Patients should be observed for evidence of glucose intolerance, hypopituitarism, malignant transformation of skin lesions, hypothyroidism, slipped capital femoral epiphysis, and intracranial hypertension.
The finding of higher FDG uptake in the pituitary gland of PTSD sufferers supports the theory that many veterans diagnosed with PTSD may actually have hypopituitarism.
Nonfunctional pituitary tumors may result in varying degrees of hypopituitarism or progressive bitemporal visual field loss; hormone-secreting pituitary tumors cause pathological syndromes such as acromegaly, Cushing disease (hypercortisolism), and thyrotoxicosis.
Dylan, diagnosed with gland condition hypopituitarism last May, will raise money for Ty Hafan, Breast Cancer Care and the Sikusi school in Uganda which is twinned with Dylan's school, Maesybryn Primary School, Llantwit Fardre, as part of the challenge, which will see him cycle the distance on his modified turbo trainer alongside school friends.
11) Because the pituitary gland in the brain is the "master gland" regulating other hormones, brain trauma has been linked to hypopituitarism (underfunctioning of the pituitary gland) which reduces the secretion of a number of hormones.
In TSHomas, hyperthyroidism and goiter are present; symptoms of cephalalgia, visual field defect and hypopituitarism can also be observed (1), (7).