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interleukin-1 |
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interleukin-1 [‚in·tər¦lük·ən ′wən]
(immunology) A cytokine produced by macrophages, endothelial cells, lymphocytes, and epidermal cells that plays roles in the inflammatory process and in the immune response. Abbreviated IL-1. Want to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit the webmaster's page for free fun content. |
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No references found | Drugs like Enbrel, Humira, and Remicade block the effects of TNF while Kineret blocks the effects of IL-1. Current therapy targeting IL-1 in rheumatoid arthritis (RA) is based on a recombinant form of the IL-1 receptor antagonist (IL-1Ra; anakinra), which binds to the IL-1 receptor without eliciting a signal and therefore competes with the binding of the two natural ligands, namely IL-1a and IL-1U. |
IL-1 |
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