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interleukin-13
(redirected from IL-13)

   Also found in: Medical 0.01 sec.
interleukin-13 [‚in·tər¦lük·ən ′thər‚tēn]
(immunology)
A cytokine produced by activated T lymphocytes that inhibits inflammatory cytokine production induced by bacterial endotoxin and stimulates gamma-interferon production by natural killer cells, enhancing the effect of interleukin-2. Abbreviated IL-13.


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IFN-[gamma] predominates over IL-4 in chronic skin lesions and older patch test reactions, whereas, IL-5 and IL-13 still remain at high levels (34-36).
An in vitro study employing human peripheral blood basophils demonstrated that forskolin, functioning as a phosphodiesterase inhibitor, significantly suppressed the release of cytokines IL-4 and IL-13 that are secreted by the basophils after the cross-linking of cell surface immunoglobulins.
numerous studies have shown that IL-4, IL-5 and IL-13 secretion .
 
 
 
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