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(myocardosis), a term often applied to a broad group of heart diseases; specifically, noninflammatory lesions of the heart muscle (myocardium) resulting from a disturbance in myocardial metabolism. Among the causes of cardiomyopathy are nutritional disorders (alimentary dystrophy and avitaminosis, for example); protein metabolism disorders in hepatic or renal insufficiency and podagra; disturbances of carbohydrate metabolism (diabetes mellitus) and electrolyte metabolism; and endocrine disorders such as those associated with thyrotoxicosis and with hypoxia in impairment of coronary circulation, anemia, and mountain sickness. Myocardosis may also be caused by overstraining the myocardium and by exogenous poisons, such as carbon monoxide and alcohol.

In many cases the patient has no specific symptoms in the early stages; however, there may be shortness of breath and disagreeable sensations in the heart. Cardiomyopathy is manifested by dull, distant heart sounds, electrocardiographic changes, systolic murmur, extrasystole, and, more rarely, other types of arrhythmia. Severe cardiomyopathy weakens the heart contractions and may cause cardiac insufficiency. The changes associated with cardiomyopathy are usually reversible and disappear with the elimination of the underlying disease.

The cure includes treatment of the underlying disease and administration of agents that improve metabolic processes in the myocardium.


Kedrov, A. A. Bolezni myshtsy serdtsa. Leningrad, 1963.


References in periodicals archive ?
Idiopathic dilated cardiomyopathy in dogs: survival and prognostic indicators.
In the current study, we prospectively assessed the long-term safety of ivabradine in efficiently reducing HR to 60 bpm in patients with idiopathic dilated cardiomyopathy using several parameters.
The alpha(2C) Del322-325 adrenergic receptor polymorphism is not associated with heart failure due to idiopathic dilated cardiomyopathy in black Africans.
Electrocardiographic and cardiac magnetic resonance imaging parameters as predictors of a worse outcome in patients with idiopathic dilated cardiomyopathy.
Skudicky D, Bergemann A, Sliwa K, Candy G, Sareli E Beneficial effects of pentoxifylline in patients with idiopathic dilated cardiomyopathy treated with angiotensin-converting enzyme inhibitors and carvedilol: results of a randomized study.
Idiopathic dilated cardiomyopathy is a common cause of heart failure in which the ventricles of the heart weaken and dilate for unknown reason.
Objective: We aimed to evaluate coronary blood flow by means of the TIMI (Thrombolysis in Myocardial Infarction) frame count in patients with idiopathic dilated cardiomyopathy who had angiographically proven normal coronary arteries and compare the results with those of healthy subjects.
Eighteen children (mean age, 10 years) with idiopathic dilated cardiomyopathy received 9.
Furthermore, in chronic, nonischemic cardiac conditions, such as idiopathic dilated cardiomyopathy, increased troponin T concentrations were found to correlate with a short-term unfavorable prognosis (9), and cardiac troponin T has been reported to be progressively released in advancing stages of heart failure (10).
The patient was a 72-year-old woman suffering from idiopathic dilated cardiomyopathy, an enlargement of the heart of undetermined origin that negatively affects the heart's pumping ability and may damage the heart's electrical conduction system.
Medium-term effectiveness of L-thyroxine treatment in idiopathic dilated cardiomyopathy.

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