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She was diagnosed with idiopathic thrombocytopenia, an autoimmune disorder that also affects humans.
GSK described the phase II studies well underway in three major indications: idiopathic thrombocytopenia purpura (ITP), hepatitis C (HCV) and chemotherapy-induced thrombocytopenia (CIT).
Prevalent clinical disorders where platelet loss or dysfunction leads to significant morbidity include idiopathic thrombocytopenia purpura (ITP), myelodysplastic syndrome, liver dysfunction associated with hepatitis C viral and severe cirrhosis, chemotherapy-induced thrombocytopenia (CIT) as well as a number of other disorders.
Prevalent clinical disorders where platelet loss or dysfunction leads to significant morbidity include idiopathic thrombocytopenia purpura (ITP), myelodysplastic syndrome (MDS), liver dysfunction associated with hepatitis C viral and severe cirrhosis, and chemotherapy-induced thrombocytopenia (CIT) as well as a number of other disorders.
Anthera's Phase 3 development product candidate, blisibimod, targets elevated levels of B-cell activating factor, or BAFF, which has been associated with a variety of B-cell mediated autoimmune diseases, including systemic lupus erythematosus (SLE), or lupus, Immunoglobin A nephropathy, or IgAN, lupus nephritis, vasculitis, rheumatoid arthritis, idiopathic thrombocytopenia purpura, and others.
Idiopathic thrombocytopenia and GBS share both triggering and therapeutic factors; antineural antibodies have been demonstrated in both.
Coagulopathies can also be acquired in pregnancy These include idiopathic thrombocytopenia, thrombocytopenia associated with preeclampsia, or disseminated intravascular coagulation associated with fetal demise or amniotic fluid embolus, he said during the meeting.
Antibody binding to platelet antigens in acute and chronic idiopathic thrombocytopenia purpura: a platelet membrane ELISA for the detection of antiplatelet antibodies in serum.

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