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idiotype
(redirected from Idiotypes)

    Also found in: Dictionary/thesaurus, Medical, Wikipedia 0.01 sec.
idiotype [′id·ē·ə‚tīp]
(immunology)
The unique amino acid sequence and corresponding three-dimensional structure of the variable region of an immunoglobulin molecule that determines its antigenic specificity.
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This test involves separation of EPO idiotypes by isoelectric focussing, immunoblotting, and detection of IgG labeled with streptiverdin-peroxidase.
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Idiotypes can provoke anti-idiotypes, which in turn can provoke anti-idiotypes that attach to the initial provoker as well as to the anti-idiotype.
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