A negative IGRA
may be a convenient 'rule-out' test for TB if the diagnostic sensitivity of the assay is sufficiently high, for example, nearly 95%.
For individuals at high risk of infection but not at high risk of disease progression, IGRA
is recommended if they have received a bacille Calmette-Guerin vaccine or are unlikely to return for TST interpretation.
There are insufficient data to recommend a preference for either a TST or an IGRA
as the first-line diagnostic test in individuals 5 years or older who are likely to be infected with Mtb, who have a high risk of progression to active disease, and in whom it has been determined that diagnostic testing for LTBI infection is warranted; either test would be acceptable.
estimated sensitivity of IGRAs
from studies of patients with active TB; persons in contact with patients with active TB who were categorised into gradients of exposure; and concordance of IGRA
and the TST.
For these calculations, the discordance rate between the TST and IGRA
was arbitrarily set at 30%.
Sergey Martyushov, (1) Ozer Igra
, (2,3) and Tov Elperin (2)
The marker was subsequently assessed in the two CD 235RR x Igra
RA 518 RR (145 lineages [F.
laboratories are at the forefront of expanding IGRA
testing as the ambitious 2050 goal of TB elimination rapidly approaches.
Livadary attended a "straight" rodeo event in Colorado and sat next to a lesbian couple, who told him about the IGRA
For example, the decade from 1990-2000 reflects the non-compacted gaming years in the state after IGRA
Summing up the area between the curves and using a constant number of 877 records in IGRA
from 1971 onward gives an additional contribution of ERA-CLIM to the number of assimilated upper-air records x months in ERA-40 (-415,000) of 15.
test was developed in the last 10-15 years and diagnoses a latent TB infection.