immunoglobulin A deficiency


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immunoglobulin A deficiency

[‚im·yə·nō‚gläb·yə·lən ¦ā di′fish·ən·sē]
(immunology)
An immune system disorder in which lower than normal amounts of immunoglobulin A are produced, resulting in increased susceptibility to infections such as chronic sinusitis, chronic pulmonary infections, and digestive problems.
References in periodicals archive ?
Hizentra is contraindicated in individuals with a history of anaphylactic or severe systemic response to immune globulin preparations or components of Hizentra, and in persons with selective immunoglobulin A deficiency who have known antibody against IgA and a history of hypersensitivity.
As with all immunoglobulin products, Vivaglobin is contraindicated in individuals with a history of anaphylactic or severe systemic response to immunoglobulin preparations, in the US and Canada also and in persons with selective immunoglobulin A deficiency who have known antibody against IgA.
As with all immune globulin products, the study medication is not recommended for individuals with a history of anaphylactic or severe systemic response to immune globulin preparations and in persons with selective immunoglobulin A deficiency who have known antibody against IgA.