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proteasome
(redirected from Immunoproteasome)

   Also found in: Wikipedia 0.01 sec.
proteasome [′prōd·ē·ə‚sōm]
(biochemistry)
A large proteolytic particle found in the cytoplasm and nucleus of all eukaryotic cells that is the site for degradation of most intracellular proteins.


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Some subjects discussed are molecular chaperones in normal and pathologic states, genetic polymorphism of immunoproteasome and its functional value, and genetic polymorphism of alpha-1-inhibitor of proteinases and its clinical value.
Thus, basic questions such as those related to possible consequences, for immune responses in infectious diseases and cancer, of age-related alterations of antigen processing and presenting, change with age of self-antigen repertoire, and the genetic basis of immunoproteasome activity and its change with age, remain largely unanswered.
 
 
 
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