indirubin


Also found in: Dictionary, Wikipedia.

indirubin

[‚in·də′rü·bən]
(organic chemistry)
Mentioned in ?
References in periodicals archive ?
While pgCAR was activated by the other seven compounds, Indirubin, Chlorogenic acid, Vitamin C, Folate, Sitosterol, Oleanolic acid and Vitamin E, which showed that reporter gene expression was activated above the DMSO control by 1.
In an alkaline environment, indoxyl turns into indigo (blue color) and indirubin (red color) pigments, which combine with catheter tubing to give the characteristic purple appearance.
This increase in "raw materials" provides increased levels of indigo and indirubin responsible for the appearance of PUBS.
This phenomenon is due to the presence of indigo and indirubin in the collected urine.
3] This is excreted and broken down in the urine by bacteria possessing one or both enzymes, sulphatise and phosphatase that metabolize this pigment to indirubin and indigo in an alkaline environment (urine).
Solove Research Institute (OSUCCC - James) - discovered that the compound, indirubin, both blocks the migration of glioblastoma cells, preventing their spread to other areas of the brain, and the migration of endothelial cells, preventing them from forming the new blood vessels that the tumor needs to grow.
Scientists have discovered that indirubin is able to help block the division of cancerous cells, which could give the plant a whole new future.
Laurent Meijer, of the Roscoff Biological Station in France, found the active ingredient was a red pigment called indirubin which reduces the protein needed when cells multiply.
In alkaline environment, indoxyl turns into indigo and indirubin pigments that combine with catheter tubing to give purple appearance.
Indirubin inhibits tumor growth by antitumor angiogenesis via blocking VEGFR2-mediated JAK/STAT3 signaling in endothelial cell.
Indigo naturalis and its active component, indirubin, have been used for decades in China to treat systemic psoriasis and leukemia (Xiao et al.