Inhibitor

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inhibitor

[in′hib·əd·ər]
(aerospace engineering)
A substance bonded, taped, or dip-dried onto a solid propellant to restrict the burning surface and to give direction to the burning process.
(chemistry)
A substance which is capable of stopping or retarding a chemical reaction; to be technically useful, it must be effective in low concentration.

Inhibitor

 

a circuit having m + n inputs and a single output, at which a signal can appear only when there are no signals on the m inputs (inhibiting). The other n inputs (principal) form one of the two logic connections, “AND” or “OR.” Inhibitors are used extensively in computers. They are very often understood to be a circuit having a single principal input and a single inhibiting input. A signal appears at the output of such a circuit when a signal is present on the principal input but there is none on the inhibiting input. Such an inhibitor is called an anticoincidence gate; its conventional representation is given in Figure 1.

Figure 1. Block diagram of an anticoincidence gate (inhibitor) with m — 1 and n 1:(A) principal input, (Q) inhibiting input, (Ga) anticoincidence gate

inhibitor

A substance added to paint to retard drying, skinning, mildew growth, etc. Also see corrosion inhibitor, inhibiting pigment, drying inhibitor.
References in periodicals archive ?
About one third of HIV-positive people studied at Albany Medical Center had an important drug-drug interaction involving one of the medications in a first antiretroviral combination that included a protease inhibitor (PI), a nonnucleoside (NNRTI), or the integrase inhibitor Isentress (raltegravir).
Broad antiretroviral activity and resistance profile of the novel human immunodeficiency virus integrase inhibitor elvitegravir (JTK-303/GS-9137).
The safety profile is based on pooled data from Phase IIb and Phase III clinical studies in 980 previously untreated patients, 357 previously treated patients unexposed to integrase inhibitors and 234 patients with prior treatment failure that included an integrase inhibitor (including integrase class resistance).
Integrase inhibitors, the latest weapon in the HIV treatment armamentarium, stop HIV from incorporating its genetic information into the DNA of an infected T cell, essentially heading off HIV's master plan to hijack all future generations of cells.
S/GSK1349572, which is being developed by GlaxoSmithKline, is an other second-generation integrase inhibitor that may be headed to phase II/III clinical trials.
The protease inhibitor Prezista and the integrase inhibitor Isentress could be detected in all CSF samples analyzed in separate studies of people taking these, anti-retrovirals.
ViiV Healthcare's first investigational once-daily single-tablet regimen, combining the integrase inhibitor dolutegravir and nucleoside analogues abacavir/lamivudine
Standard HIV-drug therapy contains three active components: a backbone of two NRTIs, plus either a Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI), Protease Inhibitor (PI) or Integrase Inhibitor (INI).
It is a human immunodeficiency virus type 1 (HIV-1) integrase inhibitor.
SAN FRANCISCO -- For the first time, an integrase inhibitor is included in the preferred first-line antiretroviral regimens for adolescents and adults with HIV, and another integrase inhibitor may be starting phase II/III clinical trials.