intercalating agent

intercalating agent

[‚in·tər′ka‚lād·iŋ ‚ā·jənt]
(cell and molecular biology)
A chemical substance that can insert itself between base pairs in a deoxyribonucleic acid molecule.
References in periodicals archive ?
During agarose gel electrophoresis, plasmid pBR322 the drug-free DNA is negatively supercoiled and migrates through the gel as a single band, but its profile changes significantly in the presence of an intercalating agent (EtBr).
Pillarisation and intercalation process of the clay was carried out by mixing bentonite, pillaring agent solution and intercalating agent (hexadecyltrimethylammonium-bromide; HDTMA-Br) with ratio [gram bentonite/ volume of solution] = 1 gram/50 mL.
Some researchers have studied the corrosion resistance of polystyrene (PS)-clay and poly (styrene-co-acrylonitrile) (PSAN) nanocomposites with quaternary alkyl ammonium salt as an intercalating agent.
Single-stranded DNA was immobilized by covalent binding to HEG linkers on fused silica optical fibres, and hybridization was detected using the fluorescent intercalating agent ethidium bromide.
5 g/L) was used as a typical intercalating agent with major binding (100%) capability.
They concluded that the intercalating agent has a significant effect on the intercalation and exfoliation behavior of clay into the resin matrix.
BBR 2778 is an intercalating agent with reduced cardiotoxicity conceived and developed by Novuspharma in collaboration with the University of Vermont (UVM).
BBR 2778 is Novuspharma's novel intercalating agent currently in Phase III clinical trials for the treatment of Non Hodgkin's lymphoma.
In this case, the barrier properties improvement merely depends on the diffusion, rather than solubility (Table 4): carvacrol, acting as an intercalating agent, promotes swelling of the clay platelets, thus increasing the average aspect ratio of the inclusions.
A commercial monoamine, polyoxyalkyle-neamine (Jeffamine[R] M600, Huntsman, Woodlands, TX), was used as an intercalating agent for ZrP.
The choice of the intercalating agent is first controlled by the nature of the polymer matrix.
While the organically modified clay does lead to better intercalation/exfoliation and dispersion, a high level of organic modifier brings about several disadvantages: (1) it significantly increases the cost of polymer nanocomposites, (2) it gives rise to environmental concerns, (3) it requires different types of intercalating agents to modify MMT clay for different host polymers, and (4) most importantly, the addition of the intercalating agent can lead to a significant drop in glass transition temperature ([T.