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cell adhesion molecule
(redirected from Intercellular adhesion molecule-1)

   Also found in: Wikipedia 0.04 sec.
cell adhesion molecule [¦sel ad‚hē·zhən ′mäl·ə·kyül]
(cell and molecular biology)
A class of membrane proteins comprising the outer surfaces of cell membranes in the developing nervous system that is thought to be intimately involved in guiding development during embryonic life. Abbreviated CAM.


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Thalidomide may also increase the expression of cytoadhesion molecules in myeloma cells and in the bone marrow microenvironment, such as lymphocyte function-associated antigen-1, intercellular adhesion molecule-1, and vascular cell adhesion molcules-1.
Localization of intercellular adhesion molecule-1 in middle ear cholesteatoma.
The study, "Use of Samarium-153 (QUADRAMET) to modulate phenotype and enhance killing of tumor cells" demonstrated that exposure to QUADRAMET resulted in up-regulation of surface molecules on cancer cells, including Fas (CD95), carcinoembryonic antigen (CEA), mucin 1 (MUC-1), intercellular adhesion molecule-1 (ICAM-1 or CD54), and major histocompatibility complex class I (MHC-1).
 
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