interleukin-11


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Related to interleukin-11: IL-13, Oprelvekin, IL-3, Interleukin 12, Neumega

interleukin-11

[‚in·tər¦lük·ən i′lev·ən]
(immunology)
A pleiotropic cytokine produced by bone marrow-derived fibroblasts which supports the growth of certain cell types, such as B cells, neutrophils, and platelet-producing megakaryocytes. Abbreviated IL-11.
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References in periodicals archive ?
A nucleotide variant in the promoter region of the interleukin-11 gene associated with decreased bone mineral density.
Association of interleukin-11 promoter variant with bone mineral density in pre-menopausal women.
The cellular actions of interleukin-11 on bone resorption in vitro.
Production of interleukin-11 in bone-derived endothelial cells and its role in the formation of osteolytic bone metastasis.
In a study published in the July 1 issue of the Journal of Clinical Investigation, the researchers report that mice given interleukin-11 (IL-11) after receiving an allogeneic, or non-self, bone marrow transplant were protected from the effects of graft-versus-host disease, an often debilitating condition that can follow marrow transplants.