interleukin

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Related to Interleukin-18: Il-18

interleukin

a substance extracted from white blood cells that stimulates their activity against infection and may be used to combat some forms of cancer

interleukin

[‚in·tər′lü·kən]
(immunology)
Any of a class of proteins that are secreted mostly by macrophages and T lymphocytes and induce growth and differentiation of lymphocytes and hematopoietic stem cells.
References in periodicals archive ?
Interleukin-18 (IFNgamma-inducing factor) induces IL-8 and IL-1beta via TNFalpha production from non-CD14+ human blood mononuclear cells.
Interleukin-1beta, interleukin-12 and interleukin-18 levels in gingival fluid and serum of patients with gingivitis and periodontitis.
Lv, "The protective role of interleukin-18 binding protein in a murine model of cardiac ischemia/reperfusion injury," Transplant International, vol.
Interleukin-18 as a diagnostic marker and indicator of disease severity in adult-onset Still's disease.
Blood was centrifuged for ten minutes at 13000 rpm and plasma was separated for biochemical analysis of cytokines (IL- 6 and IL-18) through enzyme-linked immunoabsorbent assay ELISA by using the diagnostic kits [MBL for interleukin-18 and Invitrogen CMC0063 for interleukin 6] following manufacturer's recommendations.
Detectable levels of interleukin-18 in uterine luminal secretions at oocyte retrieval predict failure of the embryo transfer.
Interleukin-18 also is prominent in chronic intestinal inflammation associated with autoimmune disorders, such as inflammatory bowel disease.
There were also increased levels of interleukin-18, a cytokine produced by macrophages and associated with strong inflammatory reactions and tissue destruction.
It has also been demonstrated that resting healthy human muscles express cytokines in a fiber type specific manner, such as tumor necrosis factor (TNF)-alpha and interleukin-18 (IL-18) is solely expressed by type II fibers, whereas the expression of IL-6 in more prominent in type I compared to type II fibers (Plomgaard et al.