interleukin

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Related to Interleukin-18: Il-18

interleukin

a substance extracted from white blood cells that stimulates their activity against infection and may be used to combat some forms of cancer

interleukin

[‚in·tər′lü·kən]
(immunology)
Any of a class of proteins that are secreted mostly by macrophages and T lymphocytes and induce growth and differentiation of lymphocytes and hematopoietic stem cells.
References in periodicals archive ?
Calcineurin antagonists inhibit interferon-gamma production by downregulation of interleukin-18 in human mixed lymphocyte reactions.
A novel role for interleukin-18 in adhesion molecule induction through NF kappa B and phosphatidylinositol (PI) 3 -kinase-dependent signal transduction.
Association of common variants of vascular endothelial growth factor and interleukin-18 genes with allograft survival in renal transplant recipients of North India.
Altered expression of interleukin-18 in the ectopic and eutopic endometrium of women with endometriosis.
High-dose dexamethasone regulates interlenkin-18 and interleukin-18 binding protein in idiopathic thrombocytopenic purpura.
Interleukin-18 (IFN gamma-inducing factor) induces IL-8 and IL-1beta via TNF alpha production from non-CD14+ human blood mononuclear cells.
Interleukin-18 levels are not associated with subclinical carotid atherosclerosis in a community population: the Perth Carotid Ultrasound Disease Assessment Study (CUDAS).
Interleukin-18, the metabolic syndrome, and subclinical atherosclerosis: results from the Dallas Heart Study.
Interleukin-18 enhances atherosclerosis in apolipoprotein E(-/-) mice through release of interferon-gamma.
Genetic analysis of the interleukin-18 system highlights the role of the interleukin-18 gene in cardiovascular disease.
Chemokines and interleukin-18 are up-regulated in bronchoalveolar lavage fluid but not in serum of septic surgical ICU patients.
The researchers determined that two major plasma factors C Interleukin-18 (IL-18) and lipopolysaccharide (LPS), both markers of inflammation C may differentiate NP001 responders from non-responders.