Intermediary Metabolism


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intermediary metabolism

[¦in·tər¦mēd·ē‚er·ē me′tab·ə‚liz·əm]
(biochemistry)
Intermediate steps in the chemical synthesis and breakdown of foodstuffs within body cells.

Metabolism, Intermediary

 

intracellular metabolism; the transformation of matter in the body from the moment of its entry into the cells to the formation of the metabolic end products. The term does not refer to digestion and assimilation in the gastrointestinal tract, the formation of mineral compounds in bone tissue, or the formation of a number of other substances and fluids. The process differs in different cell organelles. Thus, glycolysis occurs predominantly in the cytoplasm, oxidative phosphorylation in the mitochondria, and protein biosynthesis in the ribosomes.

References in periodicals archive ?
The central role of rumen fermentation products in intermediary metabolism of ruminants is well recognized.
We believe that by combining known principles of ligand-field theory with new insights into organocatalysis and organo-metallic catalysis, the question of whether intermediary metabolism is a deterministic emergence from the periodic table of the elements can be systematically addressed in a series of laboratory experiments.
The present study examined the activity of enzymes of intermediary metabolism in four tissues: muscle, liver, heart and brain of three Amazonian freshwater turtles: P.
The present review analyses the possibilities for MS technique for the diagnosis of diseases related to intermediary metabolism.
Using 13C nuclear magnetic resonance (NMR) spectroscopy, the intermediary metabolism of ethanol degradation was studied in adult Drosophila, and compared with the known larval situation.
Those changes that are hidden inside the body are called intermediary metabolism.
Supply medicinal products detailed in the scope of the contract: "Neuro-psychotropic" "Typical drugs for anesthesia"; "Drugs for the treatment of diseases of the cardiovascular system"; "Drugs for the treatment of diseases of the urinary system"; "Drugs for the treatment of respiratory diseases"; "Drugs for the treatment of diseases of the digestive system"; "Drugs affecting coagulation, fibrinolysis and blood formation"; "Infusion solutions and drugs for therapeutic feeding"; "Drugs affecting intermediary metabolism and hormonoaktivni means;" "Medicines to treat infections"; "Vitamins, minerals and trace elements"; "Diagnostic tools"; "Drugs for the treatment of dermatological diseases"; "Drugs for the treatment of ophthalmic diseases"; "Other drugs"; "Extemporaneous forms.
Without going into the gory details of intermediary metabolism, it is sufficient to say that the TCA cycle produces 34 ATP molecules or 17 times that of glycolysis.
discusses intermediary metabolism at a level accessible to readers with no more than a familiarity with general biochemistry, using the long-studied microbe Saccharomyces cerevisiae yeast as a case study.
Organic acidemias are disorders of intermediary metabolism that lead to the accumulation of toxic compounds that derange multiple intracellular biochemical pathways, including glucose catabolism (glycolysis), glucose synthesis (gluconeogenesis), amino acid and ammonia metabolism, purine and pyrimidine metabolism, and fat metabolism.
In our previous work, we had data-mined genomic databases and utilized available biochemical data on metabolic pathways of several reductive chemoautotrophic organisms that included Aquifex aeolicus, Hydrogenobacter ther-mophilus, Thiomicrospira denitrificans, and Chlorobium terpidium, enabling us to construct an almost complete chart of reductive autotrophic intermediary metabolism (Sriniva-san and Morowitz, 2009).