intermediate filament

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intermediate filament

[‚int·ər′mēd·ē·ət ′fil·ə·mənt]
(cell and molecular biology)
Any of several classes of cell-specific cytoplasmic filaments of 8-12 nanometers in diameter; protein composition varies from one cell type to another.
References in periodicals archive ?
Neuronal intermediate filaments and ALS: a new look at an old question.
Desmin intermediate filament by Nova link polymer detection system was used, according to kit instructions.
As such, dystrophin constitutes a major scaffolding protein of normal muscle which links cytoskeletal actin, microtubules and intermediate filaments to the extracellular matrix.
8, Cell Marque, Rocklin, CA, USA) used and reacted with intermediate filament of cytoplasm and cell membrane.
Globoside colocalized intracellularly with intermediate filaments in a number of cell types: with vimentin in human and mouse fibroblasts, with desmin in smooth muscle cells, with keratin in keratinocytes, and with glial fibrillary acidic protein in glial cells.
Intermediate filament expression in mesotheliomas: Leimyoid mesotheliomas are not uncommon.
Keratins that form the intermediate filaments are expressed exclusively in the epithelial cells regardless of the germ layer origin of these cells.
Tumor cells usually contain intermediate filaments, have cell junctions, and may contain glycogen, dense core granules, and neurotubles.
Neoplastic cells were positive for vimentin and negative for desmin and actin and showed ultrastructural features (dilated stacks of rough endoplasmic reticulum, intermediate filaments, rare collagen secretion granules, lack of external lamina) typical of fibroblasts.
REVIEW OF INTERMEDIATE FILAMENTS, WITH SPECIAL REFERENCE TO CYTOKERATINS.
Intermediate filaments (IFs) participate in key mechanical functions and play a role in preventing excess large cell stretch.
It consists mainly of intermediate filaments called lamins and microfilaments cal led act ins and DNA topoisomeraseII (Fig.

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