segregation distorter

(redirected from Intragenomic conflict)
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segregation distorter

[‚seg·rə′gā·shən dis‚tȯr·dər]
(genetics)
An abnormality of meiosis which produces a distortion of the 1:1 segregation ratio of alleles in a heterozygote.
References in periodicals archive ?
Recently, Science Daily reported that an ongoing study by the federally funded Working Group on Intragenomic Conflict shows "that 'sexually antagonistic' epi-marks, which normally protect parents from natural variation in sex hormone levels during fetal development, sometimes carry over across generations and cause homosexuality in opposite-sex offspring.
In the current study, researchers from the Working Group on Intragenomic Conflict at the National Institute for Mathematical and Biological Synthesis (NIMBioS) integrated evolutionary theory with recent advances in the molecular regulation of gene expression and androgen-dependent sexual development to produce a biological and mathematical model that delineates the role of epigenetics in homosexuality.
The ways by which conflicts between cells and their organelles are suppressed, and more generally, the means by which organisms suppress intragenomic conflict, provide clear footprints of natural selection's importance.