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(myocardosis), a term often applied to a broad group of heart diseases; specifically, noninflammatory lesions of the heart muscle (myocardium) resulting from a disturbance in myocardial metabolism. Among the causes of cardiomyopathy are nutritional disorders (alimentary dystrophy and avitaminosis, for example); protein metabolism disorders in hepatic or renal insufficiency and podagra; disturbances of carbohydrate metabolism (diabetes mellitus) and electrolyte metabolism; and endocrine disorders such as those associated with thyrotoxicosis and with hypoxia in impairment of coronary circulation, anemia, and mountain sickness. Myocardosis may also be caused by overstraining the myocardium and by exogenous poisons, such as carbon monoxide and alcohol.

In many cases the patient has no specific symptoms in the early stages; however, there may be shortness of breath and disagreeable sensations in the heart. Cardiomyopathy is manifested by dull, distant heart sounds, electrocardiographic changes, systolic murmur, extrasystole, and, more rarely, other types of arrhythmia. Severe cardiomyopathy weakens the heart contractions and may cause cardiac insufficiency. The changes associated with cardiomyopathy are usually reversible and disappear with the elimination of the underlying disease.

The cure includes treatment of the underlying disease and administration of agents that improve metabolic processes in the myocardium.


Kedrov, A. A. Bolezni myshtsy serdtsa. Leningrad, 1963.


References in periodicals archive ?
7) 23 (82) NS Values are means [+ or -] standard deviation ACE- Angiotensin-converting enzyme inhibitors, AD- Aldosterone antagonist, ARB- Angiotensin II receptor blockers, Cu- copper; EF- Ejection fraction, ICM- Ischemic cardiomyopathy, IDCM- Idiopathic dilated cardiomyopathy, LVDD- Left ventricular diastolic diameter, LVSD- Left ventricular systolic diameter, NS- not significant, PAP- Pulmonary artery pressure, Se- selenium; Zn- zinc Table 3.
Nevertheless, some groups have reported that the outcome of cTnAAb-positive patients was not inferior or was even better than that of cTnAAb-negative patients with ischemic cardiomyopathy, dilated cardiomyopathy, heart failure, and/or ACS (6, 16-19).
Short-and long-term beneficial effects of trimetazidine in patients with diabetes and ischemic cardiomyopathy.
Neither patient underwent a cardiac stress test or cardiac catheterization to evaluate for coronary artery disease (CAD) and ischemic cardiomyopathy could not be conclusively ruled out.
In idiopathic dilated cardiomyopathy, the delayed longitudinal contraction tend to be located in the LV lateral and posterior walls; in contrast, in ischemic cardiomyopathy delayed longitudinal contraction is more frequent in the septum and in the inferior wall (33).
A 45-year-old man with past coronary artery bypass grafting, ischemic cardiomyopathy, and biventricular ICD presented after experiencing multiple shocks from his ICD.
Moreover, the data supporting the benefit of ICD in patients with ischemic cardiomyopathy (ICM) is much stronger than in patients with NICM and evidence of ischemia on cardiac catheterization will favor the use of ICD in selected high-risk populations.
The patient's Death Certificate, completed by his attending physician, showed the cause of death as "congestive heart failure following an acute myocardial infarction stemming from his prolonged history of ischemic cardiomyopathy.
Also, two people in the low-carbohydrate group died, one of complications from hyperosmolar coma at 5 months into the study and one of sudden severe ischemic cardiomyopathy at 10 months into the study.