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isoantigen
(redirected from Isoantigens)

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isoantigen [¦ī·sō′ant·ə·jən]
(immunology)
An antigen in an individual capable of stimulating production of a specific antibody in another member of the same species. Also known as alloantigen.
Isoantigen

An immunologically active protein or polysaccharide present in some but not all individuals in a particular species. These substances initiate the formation of antibodies when introduced into other individuals of the species that genetically lack the isoantigen. Like all antigens, they are also active in stimulating antibody production in heterologous species. The ABO, MN, and Rh blood factors in humans constitute important examples. Consequently, elaborate precautions for typing are required in blood transfusion. See Antibody, Antigen, Blood groups
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Using immunohistochemistry with monoclonal antibodies to blood group isoantigens A, B, and H, we studied the effect of different fixatives on the expression of these isoantigens in tissues from different organs.
Team D: pathology, allergy & immunology, dermatology, plastic & ... by Southern Medical Journal
Intramammary lymphatic invasion in breast carcinomas: evaluation using ABH isoantigens as endothelial markers.
Prognostic Factors in Breast Cancer by Fitzgibbons, Patrick L.; Page, David L.; Weaver, Donald; Thor, Ann D.; Allred, D. Craig; Clark, Gary / Archives of Pathology & Laboratory Medicine
 
 
 
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