Borneol

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Related to Isoborneol: camphor

borneol

[′bȯr·nē‚ȯl]
(organic chemistry)
C10H17OH White lumps with camphor odor; insoluble in water, soluble in alcohol; melting point 203°C; used in perfumes, medicine, and chemical synthesis.

Borneol

 

bornyl alcohol, a secondary alcohol of the bicyclic terpene group. Borneol has an endo configuration; its isomer, called isoborneol, has an exo configuration. [The (CH3)2C group is located outside the plane of the ring.]

Borneol and isoborneol contain an asymmetric carbon atom (denoted by an asterisk), and therefore each of them exists in two optically active forms and one inactive racemic form (−, +, and ±). Borneo camphor, (+)-borneol, is contained in the secretions of the tree Dryobanalops camphora, which grows on the islands of Borneo and Sumatra, as well as in rosemary, lavender, and camphor oils. The acetate form, ( − )-borneol, is contained in the coniferous needle of the Siberian pine. Both (+)-borneol and (−)-borneol have a melting point Tm = 208.5° C, boiling point Tb = 212° C, and angle of rotation of the plane of polarization [α]D20 = ±37.9°; and both sublimate. The racemate (±)-borneol melts at 210.3° C. Both (−)-borneol and (±)-borneol are components of valerian oil.

Borneol is converted into camphor upon oxidation and catalytic dehydrogenation; the dehydration of borneol leads to camphene. The primary method of obtaining borneol is the hydration of pinene, which is contained in turpentine. Borneol is used in the production of camphor.

Isoborneol (Tm= 214° C) is not found in nature; it is obtained from camphene.

References in periodicals archive ?
Thus the presence of [alpha]-pinene, [alpha]-terpinene, [gamma]-terpinene, terpinolene, [beta]-terpineol, a-terpineol (one the major compounds in fruit extract), 4-terpineol, isoborneol, [gamma]-cadinene (the major compound in leaf extract), [alpha]-cadinene, cadina-1, 4-diene and [sigma]-cadinene may contribute to the diuretic and antiseptic action of the leaf and fruit extracts of the Egyptian J.
Composto (%) Componentes IR Sabineno 0,14 970 [beta]-Pineno 0,34 975 1,8 Cineol 5,37 1030 Linalol 71,88 1100 [alpha]-Terpineol 0,49 1194 Geraniol 13,66 1249 Acetato de isoborneol 0,23 1282 Acetato de geraniol 3,12 1376 [beta]-Elemeno 0,22 1386 [alpha]-trans-Bergamoteno 1,67 1430 Germacreno D 0,50 1477 [gamma]-Cadineno 0,49 1509 epi-[alpha]-Cadinol 1,90 1638 IR= indice de retencao.
The major components were [alpha]-pinene, camphene, [beta]-pinene, myrcene, limonene, [beta]-phellandrene, trans[beta]-terpineol, 4-allylanisole, and isoborneol.
US 6,270,752 B1: Researcher Giancarlo Verona of Milan, Italy, has patented a composition to prevent and treat hair loss that contains a hydroalcoholic mixture of beta-pinene, camphene, beta-myrcene, limonene, cineole, camphor, linalol, bornyl acetate, isobornyl acetate, menthol, terpinen-ol and isoborneol monoterpens.
ROTATORY POWER OF ISOBORNEOL AND (S)-(-)-ENDO BORNEOL AT DIFFERENT WAVELENGTH REGIONS.