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isoniazid |
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isoniazid (ī'sōnī`əzĭd), drug used to treat tuberculosis tuberculosis (TB), contagious, wasting disease caused by any of several mycobacteria. The most common form of the disease is tuberculosis of the lungs (pulmonary consumption, or phthisis), but the intestines, bones and joints, the skin, and the genitourinary, ..... Click the link for more information. . Also known as isonicotinic acid hydrazide, isoniazid is the most effective antituberculosis drug currently available. The drug inhibits or kills the tubercle bacilli that cause the disease. It is usually given together with some other antituberculosis drug such as streptomycin streptomycin (strĕp'tōmī`sĭn), antibiotic produced by soil bacteria of the genus Streptomyces ..... Click the link for more information. or aminosalicylic acid to prevent emergence of drug resistant organisms (see drug resistance drug resistance, condition in which infecting bacteria can resist the destructive effects of drugs such as antibiotics and sulfa drugs . Drug resistance has become a serious public health problem, since many disease-causing bacteria are no longer susceptible to ..... Click the link for more information. ). To prevent development of tuberculosis in individuals who have a positive reaction to a tuberculin skin test, isoniazid is given alone. Side effects are seen only with very high doses. isoniazid [‚ī·sə′nī·ə·zəd] (pharmacology) C6H7N3O A drug used as a tuberculostatic. Also known as isonicotinic acid hydrazide. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| Indeed, isoniazid and ethambutol, two of the primary antibiotics now used to treat tuberculosis, interfere with cell wall biosynthesis. Multidrug-resistant tuberculosis (MDRTB), defined as TB resistant to at least isoniazid and rifampin, represents an obstacle to TB control, especially in areas where MDRTB prevalence is high (1). Culture of the discharge was positive for Mycobacterium tuberculosis and sensitive to ethambutol, isoniazid, pyrazinamide, and rifampin. |
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