isosterism

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isosterism

[ī′säs·tə‚riz·əm]
(physical chemistry)
A similarity in the physical properties of ions, compounds, or elements, as a result of electron arrangements that are identical or similar.
References in periodicals archive ?
The prior art also defined isosteres as atoms in which the peripheral layers of electrons can be considered identical, as is the case for bioisosteres CH and nitrogen (N).
Paradigm Therapeutics is exploiting the use of silicon as an isostere for carbon in drug design in cases where the presence of silicon could improve the molecule's properties.