Joshua Lederberg


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Lederberg, Joshua

(lā`dərbûrg'), 1925–2008, American geneticist, b. Montclair, N.J., grad. Columbia, 1944, Ph.D. Yale, 1948. He is known for his studies of the genetic mechanisms of bacteria. He shared with G. W. BeadleBeadle, George Wells,
1903–89, American geneticist, b. Wahoo, Nebr., grad. Univ. of Nebraska (B.S., 1926; M.S., 1927), Ph.D. Cornell, 1931. Beadle taught (1931–36) biology at the California Institute of Technology, where he also began genetic research on the fruit
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 and E. L. TatumTatum, Edward Lawrie,
1909–75, American geneticist, b. Boulder, Colo., grad. Univ. of Wisconsin (B.A., 1931; M.S., 1932; Ph.D., 1935). From 1937 to 1945 he taught at Stanford and from 1945 to 1948 at Yale.
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 the 1958 Nobel Prize in Physiology or Medicine for establishing that sexual recombination occurs in bacteria. Lederberg showed that although bacteria reproduce only by dividing, they are able to effect sexual recombination by processes that result in exchange of genetic material between different bacteria. A pioneer in the fields of bacterial genetics, microbiology, and molecular biology, he taught at the Univ. of Wisconsin (1947–59) and Stanford Univ. (1959–78) and joined Rockefeller Univ. in 1978 as its president, serving until 1990.

Lederberg, Joshua

 

Born May 23, 1925, in Montclair, N.J., USA. American geneticist and biochemist.

Lederberg graduated from Columbia University in 1944 and continued his education at Yale University, where he received the doctor of philosophy degree in 1947. From 1947 to 1958 he was at the University of Wisconsin. Since 1959 he has been a professor at the Medical School of Stanford University in Palo Alto and head of its Laboratory for Molecular Medicine and simultaneously (since 1962) professor at the University of California at Berkeley. He discovered the mechanism of genetic recombination in bacteria in 1947. Lederberg was awarded the Nobel Prize in 1958 together with G. Beadle and E. Tatum for research on the genetics of microorganisms.

WORKS

“Bacterial Protoplasts Induced by Penicillin.” Proceedings of the National Academy of Sciences, 1956, vol. 42, no. 9, pp. 574–77.
“Linear Inheritance in Transductional Clones.” Genetics, 1956, vol. 41, no. 6, pp. 845–71.
“Protoplasts and L-type Growth of Escherichia coli.” Journal of Bacteriology, 1958, vol. 75, no. 2, pp. 143–60. (With St. Clair.)

Lederberg, Joshua

(1925–  ) geneticist; born in Montclair, N.J. He joined the University of Wisconsin (1947–58), moved to Stanford (1959–78), then became president of Rockefeller University (1978–90), where he remained as a professor. He shared one-half the 1958 Nobel Prize in physiology for his work as Edward Tatum's graduate student at Yale (1944–47), where he discovered that bacteria can reproduce sexually, and for his subsequent contributions to the science of bacterial genetics. His discovery of transduction in bacterial genes engendered the possibility of genetic engineering. He was a consultant for the U.S. space program, and wrote extensively on evolution and the future of humanity.
References in periodicals archive ?
The late Nobel Prize-winning molecular biologist Joshua Lederberg famously said that; and it seems particularly significant at the time of this writing, only days after the first recorded case of Ebola virus transmission within North America.
This year marks the 20th anniversary of the release of the IOM's seminal report on Emerging Infections, a study co-chaired by the late Joshua Lederberg and Robert Shope and the 15th anniversary of the creation of the Forum on Microbial Threats," stated Dr.
Joshua Lederberg, led Larry Ellison to understanding the therapeutic and market potential of biotechnology.
He did receive International recognition for this work including the nomination for the Nobel Prize by none other than Nobelist Professor Joshua Lederberg (Eugene Garfield, personal communication).
As Ian Willams writes for our next issue, "In 2002, Nobel laureate Joshua Lederberg coined the term "superorganism" to describe the ensemble of human and non-human cells that constitute our body.
Our relationship to infectious pathogens," wrote the late Joshua Lederberg, "is part of an evolutionary drama.
I am writing this column in February, and a few days ago, Joshua Lederberg died (Broad, 2008).
Geneticist and microbiologist Joshua Lederberg, PhD, winner of a Nobel Prize in 1958 for his work in bacterial genetics, died Feb.
King, literacy crusader Ruth Johnson Colvin, historian and journalist Paul Johnson and Nobel Prize-winning scientist Joshua Lederberg.
I recently had the privilege of a private meeting with Nobel Laureate Joshua Lederberg.
And we refer the avid reader and the medical scholar to the writings of Rockefeller University's distinguished emeritus president, Doctor Joshua Lederberg, who for many years has been telling us that the microbes have taken our best shot, and are now waging a massive counteroffensive against antibiotics and the other "wonder drugs" that, not so long ago, were believed to have accomplished the final solution to the microbe problem.
Tom Burroughs, Stacey Knobler, Joshua Lederberg, eds.