Karyolysis


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Related to Karyolysis: necrosis, karyorrhexis

karyolysis

[‚kar·ē′äl·ə·səs]
(cell and molecular biology)
Dissolution of a cell nucleus.

Karyolysis

 

dissolution of the nucleus of a cell; the laststage of necrobiosis (following karyopyknosis and karyorrhexis)before the death of a cell. In the karyolytic nucleus the ability to be stained is lost, since the nucleic acids break down intophosphoric acid and purine bases, which do not take up basicdyes.

References in periodicals archive ?
ONL nuclear deformations (arrows) were observed in (A) control ONL nucleus and as (B) nucleolus condensation, (C) karyolysis, (D, E pyknosis, and (F) karyorrhexis.
Necrosis of the epithelium of proximal convoluted tubules was characterized by pyknosis, karyorhexis and karyolysis.
This degeneration continued through to the end of the anoxia exposure (60 h), leading to pyknotic nuclei, karyorrhexis, karyolysis, and increased eosinophilia of the cytoplasm, with loss of distinct cell borders consistent with coagulative necrosis.
These were; contaminant bacteria and fungi, cytoplasmic inclusions, disintegrating cytoplasm, vacuolated cytoplasm, and presence of karyolysis, karyorrhexis and pyknosis.
They showed no chromatin condensation or cytoplasmatic condensation and fragmentation, indicating that the nuclear remnants were undergoing karyolysis (nuclear dissolution) (Ming-Jie et al.
After exposure of neurons to OGD 2 h and RP 12 h at 37 [degrees]C, microscopy revealed the destruction of neurons, OGD/RP-induced neuronal loss and progressive degeneration, which were characterized by karyopyknosis or karyolysis and shortage of dendrite trees.
Cell death of hepatocytes and endothelial cells during reperfusion is characterized by swelling of cells and their organelles, release of cell contents, eosinophilia, karyolysis, and induction of inflammation [1].
Whereas shrinkage of the cytoplasm, chromatin condensation, membrane blebbing and formation of apoptotic bodies characterize apoptosis; the cellular swelling and karyolysis typically occur in necrosis [21].
We also analyzed other abnormalities in the nucleus of those cells such as broken-egg, karyolysis or kariorrhexis, to see if there was some kind of genotoxicity or citotoxicity.