Ketone Bodies


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Ketone Bodies

 

a group of organic compounds (β-hydroxybutyric acid, acetoacetic acid, acetone) that are formed in the liver, accumulated in the blood (ketonemia), and excreted in the urine (ketonuria) when fatty acids are incompletely oxidized because of a metabolic disturbance associated with starvation and certain pathological states, such as diabetes mellitus. Also called acetone bodies.

References in periodicals archive ?
This raises the possibility that, if in fact exercise benefits the brain, ketone bodies may mediate some of that effect," Dr.
Moreover, Andersson (1988) reported that acetone had the highest relative concentration in milk (Table 1) and the least diurnal variation, making it the best of the three ketone bodies for ketosis testing.
50-52) In addition to the general benefits of a low-carb diet, a ketogenic diet offers several supplementary advantages: during the catabolism of triglycerides and fatty acids to create ketone bodies in substitution for glucose, the liver will convert glycerol (the backbone of the triglyceride) and protein into glucose through a process called gluconeogenesis, which requires a significant amount of energy (increased caloric expenditure).
Ketone bodies will be seen in the blood and urine (ketonuria), and they are responsible for the sweet fruity breath odor.
The use of alternative substrates, such as ketone bodies and lactate, in the brain may contribute to the lack of symptoms related to hypoglycaemia in these situations.
The glycolytic potential is similar to all sampled species, but amino acid and ketone bodies metabolism are consistent with high protein diet in P.
The breakdown of fats results in the production of ketone bodies as a by-product.
Patients' maternal ketone bodies and glycemia were measured immediately after randomization into the intervention or control group and at the end of the first stage of labor using the Precision Xtra system.
With Ketasyn, scientists have devised a way to provide the cells with another energy source, ketone bodies, to replace the scarce glucose.
Ketone bodies In diabetic ketoacidosis, alcoholism, starvation Lactic acid In circulatory or respiratory failure, sepsis, ischemic bowel or limb, seizures, malignancy, hepatic failure, CO poisoning, or cyanide poisoning Formic acid In methanol poisoning Oxalic acid In ethylene glycol poisoning Salicylic acid In aspirin poisoning Accumulation of organic anions In renal failure such as phosphates and sulfates Table 2.
Coincidentally, the level of volatile fatty acids in blood rose, and glucose and concentration of ketone bodies declined.