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Klinefelter's syndrome

   Also found in: Dictionary/thesaurus, Medical, Wikipedia, Hutchinson 0.01 sec.
Klinefelter's syndrome [′klīn‚fel·tərz ‚sin‚drōm]
(medicine)
A complex of symptoms associated with hypogonadism in males as an accompaniment of an anomaly of the sex chromosomes; somatic cells are found to have a Y chromosome and more than one X chromosome.


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The study sample of 37 participants includes ten persons with complete androgen insensitivity (CAIS), five with partial androgen insensitivity (PALS), four women with CAH, two women with progestogen-induced clitoromegaly, one each of Klinefelter's syndrome in a male and Turner's syndrome in a female, six miscellaneous patients including gonadal dysgenesis, micropenis, true hermaphroditism, and at least two with hypospadias, plus eight for whom the diagnosis is unknown.
I was diagnosed 12 years ago with Klinefelter's syndrome, which has as a symptom low testosterone ("Unproven Elixir," SN: 5/10/03, p.
Chromosomal problems such as Down's syndrome, Turner's syndrome, or Klinefelter's syndrome are not inherited in the sense that a parent must either have the condition or be a carrier of the corresponding genes; rather, such conditions result from errors in the transmission of genetic material.
 
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