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Koch, Robert

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Koch, Robert (rō`bĕrt kôkh), 1843–1910, German bacteriologist. He studied at Göttingen under Jacob Henle Henle, Jacob (Friedrich Gustav Jakob Henle) (frē`drĭkh g
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. As a country practitioner in Wollstein, Posen (now Wolsztyn, Poland), he devoted much time to microscopic studies of bacteria, for which he devised not only a method of staining with aniline dyes but also techniques of bacteriological culture still in general use. He established the bacterial cause of many infectious diseases and discovered the microorganisms causing anthrax (1876), wound infections (1878), tuberculosis (1882), conjunctivitis (1883), cholera (1884), and other diseases. He was professor at the Univ. of Berlin from 1885 to 1891 and head of the Institute for Infectious Diseases (founded for him) from 1891 to 1904. In the course of his bacteriological investigations for the British and German governments he traveled to South Africa, India, Egypt, and other countries and made valuable studies of sleeping sickness, malaria, bubonic plague, rinderpest, and other diseases. For his work in developing tuberculin as a test for tuberculosis he received the 1905 Nobel Prize in Physiology or Medicine.

Koch, (Heinrich Hermann) Robert

(born Dec. 11, 1843, Clausthal, Hannover—died May 27, 1910, Baden-Baden, Ger.) German physician. As the first to isolate the anthrax bacillus, observe its life cycle, and develop a preventive inoculation for it, he was the first to prove a causal relationship between a bacillus and a disease. He perfected pure-culture techniques, based on Louis Pasteur's concept. He isolated the tuberculosis organism and established its role in the disease (1882). In 1883 he discovered the causal organism for cholera and how it is transmitted and also developed a vaccination for rinderpest. Koch's postulates remain fundamental to pathology: the organism should always be found in sick animals and never in healthy ones; it must be grown in pure culture; the cultured organism must make a healthy animal sick; and it must be reisolated from the newly sick animal and recultured and still be the same. Awarded a Nobel Prize in 1905, he is considered a founder of bacteriology.



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