Kozak sequence

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Kozak sequence [′kō‚zak ‚sē·kwəns]

(cell and molecular biology)

A nucleotide sequence in the 5′ untranslated messenger ribonucleic acid region that allows ribosomes to recognize the initiator codon.

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Variability in these regions, especially in the so-called KOZAK sequence around the start codon (33), may influence efficiency of translation initiation and, thus, protein expression and virus production.

Imported Lassa Fever in Germany: Molecular Characterization of a New ... by Schmitz, Herbert / Emerging Infectious Diseases

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