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Krebs, Edwin

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Krebs, Edwin, 1918–, American biologist. He and fellow Univ. of Washington professor Edmond Fischer Fischer, Edmond H., 1920–, American biologist, b. Shanghai, China. As researchers at the Univ. of Washington in Seattle, Fischer and Edwin G. Krebs discovered a biological regulatory mechanism, reversible protein phosphorylation, that affects nearly all human
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 discovered a biological regulatory mechanism, reversable protein phosphorylation, that affects nearly all human cells. For their work, Krebs and Fischer shared the 1992 Nobel Prize in Physiology or Medicine.

Krebs, Edwin (Gerhard)

(born June 6, 1918, Lansing, Iowa, U.S.) U.S. biochemist. He received his medical degree from Washington University. With Edmond H. Fischer (b. 1920), he won a 1992 Nobel Prize for the discovery of reversible protein phosphorylation, a biochemical process that regulates the activities of proteins in cells and governs countless processes necessary for life. Errors in protein phosphorylation have been implicated in such diseases as diabetes, cancer, and Alzheimer disease.



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