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Elevation of the leukocyte count to values above the normal limit.



an increase in the absolute number of leukocytes in the peripheral blood.

Physiological leukocytosis occurs after eating and physical exertion. Symptomatic pathological leukocytosis develops with suppurative and inflammatory processes and with a number of infectious diseases, whether produced by specific causative agents of infection or as a result of the bone-marrow reaction to the breakdown of tissues caused by toxic agents or circulatory disorders (for example, myocardial infarction). Transient leukocytosis may result from the release of leukocytes into the blood from bone marrow or other tissues (for example, in stress). In all cases, the leukocytosis is reactive and disappears when its cause disappears. Leukocytosis may be produced by a malignant proliferation of hematopoietic tissue, as in leukemia.


Kassirskii, I. A., and G. A. Alekseev. Klinicheskaia gematologiia, 4th ed. Moscow, 1970.
References in periodicals archive ?
Induction of the EAC-tumor in mice was associated with some cellular, molecular, and biochemical events, such as leukocytosis, rise in serum levels of C-reactive protein (CRP), and augmented production of lipid peroxides.
In conclusion despite the very low frequency of secondary hematological malignancies in the setting of childhood acute lymphoblastic leukemia and lymphoblastic NHL the clinician should always be aware of this possibility when unexplained cytopenia or leukocytosis occurs without evidence of a relapse of the primary disease.
Sensitivity, specificity, positive and negative predictive value of leukocytosis, granulocytosis, urinalysis, and abdominal X-ray, US and serum amylase level are summarized in table 3.
Occult pneumonias: empiric chest radiographs in febrile children with leukocytosis.
Laboratory findings of elevated hematocrit and hemoglobin levels, dramatic leukocytosis left shift with increased band forms greater than 10%, and positive culture or nucleic acid-based microbial testing for C.
Approximately 600 cases of SHML have been described in the English literature, generally children or young adults with tumoral cervical adenopathy, fever, hypergammaglobulinemia, an increased erythrocyte sedimentation rate (ESR), and leukocytosis with neutrophilia.
stroke, leukocytosis, and hemoglobin less than 7 grams per deciliter
High fever with leukocytosis and raised CRP strongly indicated that infection was occurring.
The presence of renal insufficiency and leukocytosis had a negative influence on the evolution.
Given the patient's progressive symptoms and mild leukocytosis, the physician ordered a computed tomography (CT) scan of the abdomen and pelvis with contrast.
Tumor-related leukocytosis is linked with poor prognosis in patients with lung carcinoma.