Leydig cell


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Related to Leydig cell: spermatogenesis, Leydig cell tumor

Leydig cell

[′lī·dig ‚sel]
(histology)
One of the interstitial cells of the testes; thought to produce androgen.
References in periodicals archive ?
Male Sprague-dawley rats exposed to in utero di(n-butyl) phthalate dose dependent and age-related morphological changes in Leydig cell smooth endoplasmic reticulum.
It has been shown that reactive oxygen species (ROS) can inhibit the steroid hormone production of cultured leydig cells by directly affecting the steroidogenic enzymes.
Kovacevic, "Atrazine oral exposure of peripubertal male rats downregulates steroidogenesis gene expression in Leydig cells," Toxicological Sciences, vol.
Morphofunction features two compartments: (i) interstitial or intertubular, containing cells and fibers of connective tissue, blood and lymphatic vessels and Leydig cells, the main source of androgen in the body, (ii) tubular, formed by seminiferous tubules, which are structured with its outer portion to the internal: tunica propria, the seminiferous epithelium and lumen (ROOIJ, 1998).
Journal of Biomedicine and Biotechnology: Endocrine Disruptors and Leydig Cell Function, Volume 2010 (2010), Article ID 684504
The mutation was absent in the testicular, juvenile GCT; the Leydig cell tumors; and the Sertoli-Leydig cell tumors.
Increased proliferation but decreased steroidogenic capacity in Leydig cells from mice lacking cyclin-dependent kinase inhibitor 1B," Biology of Reproduction 80(6): 1232-1238.
16% 270% (c) Treatment Leydig Cell Nuclear Differential Counts Area ([micro] Mature Degenerated Fibroblast [m.
Possible significance for Leydig cell insufficiency in alcohol addiction.
Work of Pitteloud et al suggests that the effects are just not testosterone related but closely tied to restimulation of Leydig cell synthesis of testosterone.
Inflammatory cytokines have an inhibitory effect on Leydig cell steroidogenesis, altering 3(3-hydroxysteroid dehydrogenase.