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Limulus

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Limulus [′lim·yə·ləs]
(invertebrate zoology)
The horseshoe crab; the type genus of the Limulacea.


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This species is also gathered for biomedical companies because its copper-containing blood is used to create a pharmaceutical product, Limulus amoebocyte lysate (LAL) that is used to detect pathogenic endotoxins on medical devices and in injectable drugs (Novitsky, 1984; Mikkelsen, 1988; Levin et al.
This assay utilizes the highly sensitive and specific reactivity of Limulus Amebocyte Lysate to detect minute quantities of (1[right arrow]3)-[beta]-D-Glucan, which is normally found at low levels in the blood of a healthy human.
Among their topics are the epidemiological evidence, glucan-induced pulmonary inflammation in rats, organ distribution and degradation mechanisms of fungal beta-glucans in the body, and detecting and measuring the glucans with limulus amebocyte lysate-based reagents.
 
 
 
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