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scleroderma |
Also found in: Medical, Wikipedia, Hutchinson | 0.02 sec. |
sclerodermaor progressive systemic sclerosisChronic disease that hardens the skin and fixes it to underlying structures. Swelling and collagen buildup lead to loss of elasticity. The cause is unknown. It usually begins at age 25–55, more often in women, with severe inflammation of underlying tissue and stiffness, pain, and skin tautness and thickening. Systemic problems that may arise years later include fever, trouble in breathing, fibrous tissue in the lungs, inflammation of heart muscle or membranes, gastrointestinal disorders, and kidney malfunction. Calcium deposits build up under the skin. The disease may finally stabilize or gradually regress. Steroids may help, and physical medicine and rehabilitation with heat, massage, and passive exercise (movement of the limbs by the therapist) help prevent limb fixation and deformity. scleroderma [‚skler·ō′dər·mə] (medicine) An abnormal increase in collagenous connective tissue in the skin. Also known as chorionitis; dermatosclerosis; scleriasis. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| ? Mentioned in | ? References in periodicals archive | ||
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| At present, there is no agreement as to whether PRS is a distinct entity or a clinical variant of linear scleroderma en coup de sabre. Linear scleroderma is another subset of the localized disease, which frequently starts as a streak or line of hardened waxy skin on an arm or leg or on the forehead. |
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