Linoleic Acid

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linoleic acid

[¦lin·e¦lē·ik ′as·əd]
C17H31COOH A yellow unsaturated fatty acid, boiling at 229°C (14 mmHg), occurring as a glyceride in drying oils; obtained from linseed, safflower, and tall oils; a principal fatty acid in plants, and considered essential in animal nutrition; used in medicine, feeds, paints, and margarine. Also known as linolic acid; 9,12-octadecadienoic acid.

Linoleic Acid


a monobasic carboxylic acid with two isolated double bonds, CH3(CH2)3 (CH2CH=CH)2(CH2)7COOH; a colorless oily liquid. Melting point, — 11°C; boiling point, 182°C (at 532 newtons per sq m, or 4 mm of mercury); density, 0.903 g/cm3 at 20°C.

Together with arachidonic acid and linolenic acid, linoleic acid is an irreplaceable fatty acid, necessary for normal vital activity. These acids are ingested by humans and animals with food, mainly in the form of complex lipids (triglycerides and phosphatides). A substantial quantity of linoleic acid in triglyceride form (up to 40–60 percent) is known to occur in many vegetable oils and animal fats, such as soy, cottonseed, sunflower, linseed, and hemp oils and whale blubber.

References in periodicals archive ?
The study found people with the highest levels of linoleic acid are more than a third less likely to develop Type 2 diabetes.
Nearly 90% of sunflower oil consists of unsaturated fatty acids, mostly oleic acid (18: 1) and linoleic acid (18: 2).
7 For ensuring this appropriate balance of fatty acids in cereal-based diets, it is necessary to increase the a-linolenic (n-3) acid intake and reduce the quantity of linoleic (n-6) acid obtained from the cooking oil.
Linoleic acid is present in a lot of processed foods, such as potato chips, salad dressing, and packaged sandwich meats.
One is that delta-6 desaturase, as a rate-limiting enzyme in the conversion of linoleic acid and linolenic acid to arachidonic acid, is bound competitively by CLA.
Previous research found that taking linoleic acid supplements increased lean body mass and lowered fat in the midsection.
Under normal physiological conditions, linoleic and alpha-linoleic acid, which cannot be synthesized de novo, are metabolized to ARA and DELA.
Dietary conjugated linoleic acid modulation of phorbol ester skin tumor promotion.
The analyses show that interventions using linoleic acid-rich oils failed to reduce heart disease and overall mortality even though the intervention reduced cholesterol levels.
Another defect in fatty acid metabolism in these patients is an impaired capacity to incorporate linoleic acid into cell membranes.
The determination of kinetic parameters for the cis-trans isomerisation of linoleic acids in trilinolein is interesting and will reveal whether the matrix surrounding the linoleic acid moieties play a part in affecting the kinetic parameters for the isomerisation reaction.