Lipases


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Lipases

 

enzymes of the hydrolase class that catalyze the hydrolysis of ester linkages in triglycerides, with the formation of a fatty acid and glycerol. Lipases have been discovered in animals, plants (for example, in sunflower seeds), and microorganisms.

In mammals, lipases digest (decompose) fat. They are contained predominantly in pancreatic juice, from which a pure preparation of pancreatic lipase was first isolated in 1956. They are also found in the intestinal walls and in milk. Lipoprotein lipase, which catalyzes the hydrolysis of triglycerides bonded to proteins, is found in the blood plasma. The length of the chains and the degree to which the fatty acids are unsaturated have almost no influence on the activity of a lipase. Pancreatic and lipoprotein lipases hydrolyze only emulsified fats. The hydrolysis of triglycerides catalyzed by lipases is reversible. The reverse reaction is possible by means of biosynthesis.

REFERENCE

Lipid Metabolism. New York-London, 1970.

N. V. PROKAZOVA

References in periodicals archive ?
Uso de sabugo de milho pre-tratado para a imobilizacao de lipases de Burkholderia cepacia.
The use of immobilized lipase on a suitable support increases the process financial viability, mainly due to its reuse (reaction medium separation), it improves the thermal and mechanical properties (stability at different temperatures), operational stability, storage and the enzymatic activity (Cadena et al.
Lipase and phospholipase are abundantly found in animals, microorganisms and vegetables (Ejedegba et al.
The lipolytic activity of lipase is responsible for the development of rancidity along with the deterioration of the oil (Cancino et al.
Guangdong, China), uncoated lipase (UC-LIP, from Bacillus stearothermophilus, 10,935U/g, Zhuhai Tiankai Biochemical Co.
Lipase relative activities detected in various treatments were used as a reference frame to characterize the stability of enzymes.
Pseudomonas lipases are widely used in food, pharmaceutical, detergent and textile industries for quality improvements of food items, giving proper shape to pharmaceuticals products, for removal of oil stains from fabrics by hydrolysis of fats and increase fabric absorbance, respectively (Sharma et al.
Os experimentos realizados com o objetivo de avaliar a influencia da adicao de uma fonte lipidica (borra de dende) como indutor da producao de lipases por A.
Therefore, molecular dynamics simulation studies were adopted as they have been previously used for the interfacial activation of various lipases [10].
Although tributyrin may also be employed to select lipolytic microorganisms, vegetable oils, such as olive oil, may be emulsified and used as initiators in lipases production, since they are a substrate in the selection processes (CARDENAS et al.
Each application requires unique properties with respect to stability temperature and pH dependence or ability to catalyze reactions in organic solvents which is fulfilled remarkably by lipases (Kumar et al.
thuringensis TS11BP showed maximum lipase activity after 96 hr incubation (37).