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lipase |
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lipase (lī`pās), any enzyme enzyme, biological catalyst . The term enzyme comes from zymosis, the Greek word for fermentation , a process accomplished by yeast cells and long known to the brewing industry, which occupied the attention of many 19th-century chemists. ..... Click the link for more information. capable of degrading lipid lipids, a broad class of organic products found in living systems. Most are insoluble in water but soluble in nonpolar solvents. The definition excludes the mineral oils and other petroleum products obtained from fossil material. ..... Click the link for more information. molecules. The bulk of dietary lipids are a class called triacylglycerols and are attacked by lipases to yield simple fatty acids fatty acid, any of the organic carboxylic acids present in fats and oils as esters of glycerol . Molecular weights of fatty acids vary over a wide range. The carbon skeleton of any fatty acid is unbranched. Some fatty acids are saturated, i.e. ..... Click the link for more information. and glycerol, molecules which can permeate the membranes of the stomach and small intestine for use by the body. Gastric lipase, secreted by the stomach lining, has a pH value for optimal activity around neutrality and would appear, therefore, to be essentially inactive in the strongly acid environment of the stomach. It is suggested that this enzyme is more important for infant digestion since the gastric pH in infancy is much less acid than later in life. Most lipid digestion in the adult occurs in the upper loop of the small intestine and is accomplished by a lipase secreted by the pancreas. Phospholipases are the enzymes that degrade phospholipids phospholipid (fŏs'fōlĭp`ĭd) ..... Click the link for more information. . lipase any of a group of fat-digesting enzymes produced in the stomach, pancreas, and liver and also occurring widely in the seeds of plants lipase [′lī‚pās] (biochemistry) An enzyme that catalyzes the hydrolysis of fats or the breakdown of lipoproteins. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| ATL-962 was discovered and created by Alizyme plc, and is an inhibitor of gastrointestinal lipases and an agent to treat obesity and diabetes being designed to cause weight loss by reducing the digestion and thus the absorption of fat from the diet. To determine the effect of serum lipases on MEHP, MEHHP, and MEOHP levels, DEHP-spiked (2,000 ng/mL) serum aliquots (1 mL) were incubated at 37[degrees]C. Nearly all strains secrete hemolysins, nucleases, proteases, lipases, hyaluronidase, and collagenase, which convert host tissues into nutrients required for bacterial growth (3). |
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