Lipmann, Fritz Albert


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Lipmann, Fritz Albert,

1899–1986, American biochemist, b. Germany, grad. Univ. of Berlin (M.D., 1922; Ph.D., 1927). He emigrated to the United States in 1939 and became a citizen in 1944. In 1941 he became research chemist at Massachusetts General Hospital, Boston, and in 1949 professor of biochemistry at Harvard medical school. For his discovery of coenzymecoenzyme
, any one of a group of relatively small organic molecules required for the catalytic function of certain enzymes. A coenzyme may either be attached by covalent bonds to a particular enzyme or exist freely in solution, but in either case it participates intimately in
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 A, a crucial intermediary in carbohydrate oxidation, he was awarded jointly with H. A. Krebs the 1953 Nobel Prize in Physiology or Medicine.

Lipmann, Fritz Albert

 

Born June 12,1899, in Koningsberg (present-day Kaliningrad). German-American biochemist. Member of the US National Academy of Sciences (1950) and the Royal Society of London (1962).

Lipmann graduated from the University of Berlin in 1924. He worked at the Kaiser Wilhelm Institute of Biology in Berlin from 1927 to 1931, the Rockefeller Institute in 1931 and 1932, and the Carlsberg Laboratory in Copenhagen from 1932 to 1939. In 1939, Lipmann emigrated to the USA, where he worked at Cornell University until 1941 and at Harvard University until 1949. He was a professor of biochemistry at the Massachusetts General Hospital from 1949 to 1957. Since 1957 he has been with the Rockefeller Institute.

Lipmann’s main works deal with cellular metabolism, protein biosynthesis, and the activation of sulfhydryl groups. He isolated and studied the chemical structure and biological role of coenzyme A. Lipmann was awarded the Nobel Prize in 1953.