nodule

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Related to Lisch nodules: Neurofibromatosis Type 1

nodule:

see concretionconcretion,
mass or nodule of mineral matter, usually oval or nearly spherical in shape, and occurring in sedimentary rock. It is formed by the accumulation of mineral matter in the pore spaces of the sediment, usually around a fossil or fossil fragment acting as a nucleus.
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nodule

[′näj·ül]
(anatomy)
A small node.
A small aggregation of cells.
(botany)
A bulbous enlargement found on roots of legumes and certain other plants, whose formation is stimulated by symbiotic, nitrogen-fixing bacteria that colonize the roots.
(geology)
A small, hard mass or lump of a mineral or mineral aggregate characterized by a contrasting composition from and a greater hardness than the surrounding sediment or rock matrix in which it is embedded.
(medicine)
A primary skin lesion, seen as a circumscribed solid elevation.

nodule

1. any of the knoblike outgrowths on the roots of clover and many other legumes: contain bacteria involved in nitrogen fixation
2. Anatomy any small node or knoblike protuberance
3. a small rounded lump of rock or mineral substance, esp in a matrix of different rock material
References in periodicals archive ?
Caption: Figure 2: (a) Microsection showing bundles of wavy spindle cells with serpentine nuclei in fascicles (H&E, x10x), (b) Strong S-100 positivity of tumor cells (x40x), (c) cafe au lait macule (arrow) in the back, (d) axillary freckle, (e) Lisch nodule (arrow) in slit lamp examination, and (f) father of patient with multiple cutaneous neurofibromas.
Lisch nodules will appear gradually after that, followed by neurofibromas as a sign that the child is entering puberty.
Other investigations should include pure-tone audiometry to exclude bilateral neural hearing loss, an ophthalmologic examination to look for Lisch nodules (iris hamartoma), CT or MRI of the head and neck to search for other tumors (e.
CLEVELAND -- Both parents of an infant with cafe au lait spots should undergo an expert ophthalmic examination with a slit lamp to see if Lisch nodules are present, Dr.
4] Lisch nodules (dome-shaped, pigmented nodules of the iris) are present in over 90% of type 1 patients by the age of 5 years.
Detailed examination of the patient for the evidence of Neurofibromatosis revealed no neurofibromas in other locations, no "cafe au lait" spots, Lisch nodules, axillary or inguinal freckling, sphenoid wing dysplasia or thinning of the cortex of long bone, and optic glioma.
Lisch nodules [Figure 3) can be easily seen by slit lamp examination, by focusing on the anterioT surface of the iris.
Hamartomas of the iris (melanocytic nevi) can be seen and are called Lisch nodules.